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Throughout the stages of aging, cells begin to lose their ability to repair themselves and produce strong antioxidants

Araujo APB, Vargas G, Hayashide LdS, Matias I, Andrade CBV, de Carvalho JJ, Gomes FCA, Diniz LP (2024) Aging promotes an increase in mitochondrial fragmentation in astrocytes

Atefi et al., 2020

This failure mainly leads to increased production of ROS, which can damage mitochondrial components (44)

Experiments on cell proliferation have demonstrated that straight incubation of adipocytes with MG leads to enhanced cell proliferation [120], suggesting the potential involvement of MG in the development of adipose tissue in obesity (Figure 4)